MU Chemistry


Our group has been involved in the preparation of fluorescent sensors for detection of biologically important organic compounds in aqueous media. Fluorescent sensors are compounds which produce visible fluorescence in the presence of a target molecule (analyte). Such sensors have been used to visually trace the presence of certain analytes in and around cells. These studies have proven to be invaluable for the elucidation of cellular mechanisms by giving real-time information about the environment of a cell in a non-destructive manner. Our focus is on fluorescent sensors for organic analytes including neurotransmitters, carbohydrates, and certain biologically important lipids. All of these sensors are designed to function in cells using a variety of covalent and non-covalent recognition schemes. This NIH funded work involved the full range of design, synthesis and testing of each sensor system.


Timothy E. Glass • Department of Chemistry • University of Missouri - Columbia
125 Chemistry • 601 South College Ave. • Columbia, MO 65211
Tel: (573) 882-3813 • FAX: (573) 882-2754