Recent Publications

Electromyography-Driven Forward Dynamics Simulation to Estimate In Vivo Joint Contact Forces During Normal, Smooth, and Bouncy Gaits


Swithin Razu and Trent M. Guess

Abstract

Computational models that predict in vivo joint loading and muscle forces can potentially enhance and augment our knowledge of both typical and pathological gait. To adopt such models into clinical applications, studies validating modeling predictions are essential. This study created a full-body musculoskeletal model using data from the “Sixth Grand Challenge Competition to Predict in Vivo Knee Loads”. This model incorporates subject-specific geometries of the right leg in order to concurrently predict knee contact forces, ligament forces, muscle forces, and ground contact forces. The objectives of this paper are twofold: 1.) to describe an electromyography (EMG)-driven modeling methodology to predict knee contact forces, and 2.) to validate model predictions by evaluating the model predictions against known values for a patient with an instrumented total knee replacement (TKR) for three distinctly different gait styles (normal, smooth, and bouncy gait). The model integrates a subject-specific knee model onto a previously validated generic full-body musculoskeletal model. The combined model included six degrees-of freedom (DOF) patellofemoral and tibiofemoral joints, ligament forces, and deformable contact forces with viscous damping. The foot/shoe/floor interactions were modeled by incorporating shoe geometries to the feet. Contact between shoe segments and the floor surface were used to constrain the shoe segments. A novel EMG-driven feedforward with feedback trim motor control strategy was used to concurrently estimate muscle forces and knee contact forces from standard motion capture data collected on the individual subject. The predicted medial, lateral, and total tibiofemoral forces represented the overall measured magnitude and temporal patterns with good root mean squared errors (RMSEs) and Pearson’s correlation (ƿ2). The model accuracy was high: medial, lateral, and total tibiofemoral contact force RMSEs = 0.15, 0.14, 0.21 body weight (BW), and (0.92< ƿ2<0.96) for normal gait; RMSEs = 0.18 BW, 0.21 BW, 0.29 BW, and (0.81< ƿ2<0.93) for smooth gait; and RMSEs = 0.21 BW, 0.22 BW, 0.33 BW, and (0.86< ƿ2<0.95) for bouncy gait, respectively. Overall, the model captured the general shape, magnitude and temporal patterns of the contact force profiles accurately. Potential applications of this proposed model include predictive biomechanics simulations, design of TKR components, soft tissue balancing, and surgical simulation.

Other Publications

Journal Articles


Willis, B.W., Hocker, K., Razu S.,Gray, A.D., Skubic M., Sherman, S.L.., Kurkowski, S., Guess, T.M., (2018) Relationship Between Two-Dimensional Frontal Plane Measures and the Knee Abduction Angle during the Drop Vertical Jump. Journal of Sport Rehabilitation Accepted.

Razu, S., Guess, T. M., (2018). "Electromyography-Driven Forward Dynamics Simulation to Estimate In Vivo Joint Contact Forces During Normal, Smooth, and Bouncy Gaits.", Journal of Biomechanical Engineering, 2018; 140(7)

Thompson SF, Guess TM, Plackis AC, Sherman SL, Gray AD., (2018). "Youth Baseball Pitching Mechanics: A Systematic Review.", Sports Health, 2018; 10(2):133-40

Guess T.M., Razu S.S., Kuroki K., Cook J.L., (2018). "Function of the Anterior Intermeniscal Ligament.", Journal of Knee Surgery, 2018; 31(1):68-74

Gray, A. D., B. W. Willis, M. Skubic, Z. Huo, S. Razu, S. L. Sherman, T. M. Guess, A. Jahandar, T. R. Gulbrandsen, S. Miller and N. J. Siesener, (2017). "Development and Validation of a Portable and Inexpensive Tool to Measure the Drop Vertical Jump Using the Microsoft Kinect V2.", Sports Health, 2017;9(6):537-44.

Willis, B.W., Razu S., Baggett K., Jahandar A., Gray, A.D., Skubic M., Sherman, S.L.., Blecha K., Guess, T.M.,(2017). "Sex Differences in Frontal and Transverse Plane Hip and Knee Kinematics During the Modified Star Excursion Balance Test.", Human Movement, 18(3): 26-33.

Guess, T. M., Razu, S., (2017)."Loading of the medial meniscus in the ACL deficient knee: A multibody computational study.", Medical Engineering and Physics, 2017;41:26-34.

Guess, T. M., Razu, S., Jahandar, H., Skubic, M., Huo, Z., (2017). "Comparison of 3D Joint Angles Measured with the Kinect 2.0 Skeletal Tracker Versus a Marker Based Motion Capture System.", Journal of Applied Biomechanics, 33(2): 176-181.

Sherman, S. L., Gulbrandsen, T. R., Miller, S. M., Guess, T., Willis, B. W., Blecha, K. M., Hou, Z., Skubic, M., Gray, A. D. (2016). "Mass Screening of Youth Athletes for High Risk Landing Patterns using a Portable and Inexpensive Motion Sensor Device.", Orthopaedic Journal of Sports Medicine, 4(7 suppl4).

Erdemir, A., Guess, T.M., Halloran, J.P., Modenese, L., Reinbolt, J.A., Thelen, D.G., Umberger, B.R., (2016)."Commentary on the Integration of Model Sharing and Reproducibility Analysis to Scholarly Publishing Workflow in Computational Biomechanics.", IEEE Transactions on Biomedical Engineering, 63(10): 2080-2085

Guess, T. M., Razu, S., Jahandar, H., (2016)."Evaluation of Knee Ligament Mechanics Using Computational Models.", Journal of Knee Surgery, 29(02): 126-137.

Guess, T. M., Swithin, R., Jahandar, H., Stylianou, A. P., (2015)."Predicted loading on the menisci during gait: The effect of horn laxity.", Journal of Biomechanics, 48(8): 1490-1498.

Rahman, M., Cil, A., Johnson, M., Lu, Y., Guess, T. M., (2014)."Development and Validation of a Computational Multibody Model of the Elbow Joint.", Journal of Advances in Biomechanics & Applications, 1(3):169-185.

Guess, T. M., Stylianou, A. P., and Kia, M., (2014). "Concurrent Prediction of Muscle and Tibiofemoral Contact Forces During Treadmill Gait.", Journal of Biomechanical Engineering, 136(2): 021032-1-021032-9.

Kia, M., Stylianou, A. P., and Guess, T. M., (2014). “Evaluation of a Musculoskeletal Model with Prosthetic Knee through Six Experimental Gait Trials. ”, Medical Engineering & Physics, 36(3): 335-344.

Stylianou, A. P., Guess, T. M., Cook, J. L., (2014). “Development and Validation of a Multi-body Model of the Canine Stifle Joint”, Computer Methods in Biomechanics and Biomedical Engineering, 17(4): 370-377.

Lu, Y., Derakhshani, R., Pulasani, P. R., Guess, T. M., (2013). “Application of Neural Networks for the Prediction of Cartilage Stress in a Musculoskeletal System.” Biomedical Signal Processing and Control, 8(6): 475-482.

Stylianou, A. P., Guess, T. M., and Kia, M. (2013). “Multibody Muscle Driven Model of an Instrumented Prosthetic Knee During Squat and Toe Rise Motions.” Journal of Biomechanical Engineering, 135(4), 041008.

Guess, T. M., Liu, H., Bhashyam, S., Thiagarajan, G. (2013). “A Multibody Knee Model with Discrete Cartilage Prediction of Tibio-Femoral Contact Mechanics.” Computer Methods in Biomechanics and Biomedical Engineering, 16(3): 256-270.

Guess, T. M. (2012). “Forward dynamics simulation using a natural knee with menisci in the multibody framework”, Multibody Syst Dyn, 28(1): 37-53.

Bloemker, K. H., Guess, T. M., Maletsky, L. P., Dodd, K., (2012). “Computational Knee Ligament Modeling Using Experimentally Determined Zero-Load Lengths”, Open Biomed Eng J, vol. 6, pp. 33-41.

Jacobsen, R., Guess, T. M., Burks, A. (2012). “Comparing activation and recoil forces generated by epinephrine autoinjectors and their training devices” J Allergy Clin Immunol., Apr;129(4):1143-1145

Guess, T. M and A. P. Stylianou, (2012). “Simulation of Anterior Cruciate Ligament Deficiency in a Musculoskeletal Model with Anatomical Knees”, Open Biomed Eng J, vol. 6, pp. 23-32.

A. Erdemir, T. M. Guess, J. Halloran, S. C. Tadepalli, and T. M. Morrison, (2012). "Considerations for reporting finite element analysis studies in biomechanics", J Biomech, vol. 45, pp. 625-633.

Mishra, M., Derakhshani, R., Paiva, G., Guess, T. M. (2011). "Nonlinear surrogate modeling of tibio-femoral joint interactions", Biomedical Signal Processing and Control, vol. 6, pp. 164-174.

Guess, T. M., Thiagarajan, G., Kia, M. and Mishra, M. (2010). "A Subject Specific Multibody Model of the Knee with Menisci", Med Eng Phys, 32, 5 (Jun 2010), 505-515.

Tawhai M, Bischoff J, Einstein D, Erdemir A, Guess T and Reinbolt J. (2009). "Multiscale Modeling in Computational Biomechanics",IEEE Eng Med Biol Mag, 28:41-49.

Guess, T. M. and L. P. Maletsky (2005). "Computational modelling of a total knee prosthetic loaded in a dynamic knee simulator." Medical Engineering & Physics 27(5): 357-367.

Guess, T. M. and L. P. Maletsky (2005). “Computational Modeling of a Dynamic Knee Simulator for Reproduction of Knee Loading.” Journal of Biomechanical Engineering 127(7): 1216-1221.

Peer - Reviewed
Conference Proceedings


Netrrour J, Razu S, Keeney J, Guess T, “Femoral Component Malrotation Produces Quadriceps Weakness and Impaired Ambulatory Function following Total Knee Arthroplasty: Results of a Patient-Specific, Forward Dynamic Computer Model.”, American Academy of Orthopaedic Surgeons Annual Meeting. Poster Presentation. Las Vegas, Nevada, March 2019.

Echelmeyer D, Willis BW, Cox G, Leary E, Guess TM. “The Relationship Between Visual Assessment and a Single Depth Camera during the Lateral Step-down Test.” APTA, Combined Sections Meeting. Poster Presentation. Washington DC. Jan, 2019.

Ericksen B, Heberlie C, Machado M, Willis BW, Gray AD, Guess TM, Sherman SL, Mann B. “Inter-limb Asymmetries of Eccentric Mean Force during the Countermovement Jump: Sex Differences in Collegiate Athletes.” APTA, Combined Sections Meeting. Poster Presentation. Washington DC. Jan, 2019.

Machado M, Willis BW, Guess TM, Gray AD, Sherman SL, Mayhew J, Mann JB. “Examining Concentric Peak Force Asymmetries by Competitive Level, Sport, or Sex in Collegiate Athletes.” APTA, Combined Sections Meeting. Poster Presentation. Washington DC. Jan, 2019.

Machado M, Larson E, McDonnell E, Willis BW, Guess TM, Gray AD, Sherman SL, Mann B. “A Case Study: Examining Countermovement Jump Performance in a NCAA Division 1 Volleyball Player with a Baker’s Cyst” APTA, Combined Sections Meeting. Poster Presentation. Washington DC. Jan, 2019.

Willis BW, Sherman SL, Gulbrandsen T, Miller SM, Siesener N, Guess TM, Blecha K, Huo Z, Skubic M, Gray AD. “Jump Landing Mechanics of Adolescent Athletes During Ages of Peak ACL Injury Risk: Identifying Sex Differences with a Portable Motion Sensor.” 6th Annual Pediatric Research in Sports Medicine (PRiSM) Conference. Podium Presentation. Atlanta, GA. Jan, 2019.

Razu, S., Nettrour, J., Guess, T., “Femoral component axial rotation sensitivity to compartmental contact force, collateral ligament tension, and muscle forces in cruciate retaining total knee arthroplasty”, World Congress of Biomechanics 2018, Podium Presentation. Dublin, Ireland, July 2018.

Guess, T., Razu, S., “Loading on the anterior cruciate ligament during a side-cut.”, World Congress of Biomechanics 2018, Dublin, Ireland, Podium Presentation. July 2018.

Willis BW, Sherman SL, Gulbrandsen T, Miller SM, Guess TM, Siesener NJ, Blecha K, Huo Z, Skubic M, Gray AD. Sex Differences in Jump Landing Mechanics of Youth Athletes during Ages of Increased Risk for ACL Injury: Utilization of a Portable Motion Sensor. National Strength & Conditioning Association Annual Meeting. Indianapolis, IN. July, 2018.

Abbott, C., Martinez Campuzano, R., Prost, E., Guess, T., “The Effect of Walking Poles on Gait Kinematics and Kinetics in Older Adults”, APTA Conference and Exposition, Orlando, FL, June 2018

Guess, T., Hocker, K., Gray, A., Razu, S., Kurkowski, S., Sherman, S., Skubic, M., Willis, B., “The Medial Knee Position at Initial Contact of the Drop Vertical Jump is Strongly Correlated to the Knee Abduction Angle”, APTA Combined Sections Meeting, New Orleans, LA, February 2017

Echelmeyer, D., Willis, B.W., Guess, M., Sherman, S.L., Gray, A.G. Blecha, K., Guess, T.M., "Comparing Peak Hip and Knee Flexion during the Lateral Step Down Test between the Kinect V2 and Vicon: Examining Subjects with and without ACL-Reconstruction.", APTA Combined Sections Meeting, New Orleans, LA, February 2017

Razu, S., Guess, T.M., “Multi-Scale Model in Co-Simulation to Estimate Patellofemoral Contact Stress in Total Knee Replacement”, Proceedings of the 41st Annual Meeting of the American Society of Biomechanics, Boulder, CO, August 2017

Martinez, R., Abbott, C., Prost, E., Razu, S., Guess, T., “Study of Walking Effort on Elder Patients with and without the use of Walking Poles”, Orthopaedic Research Society Midwest Musculoskeletal Workshop, St. Louis, MO, July 2017

Muller, J., Razu, S., Guess. T., “Translating Patella Tendon Properties from the Open Knee in-vitro Dataset to a Computational Model”, Orthopaedic Research Society Midwest Musculoskeletal Workshop, St. Louis, MO, July 2017

Jahandar, A., Razu, S., Sherman, S., Guess, T., “Sensitivity of Patellofemoral Contact to the MPFL Ligament”, Orthopaedic Research Society Midwest Musculoskeletal Workshop, St. Louis, MO, July 2017

Larson, M., Mann, B., Jahandar, A., Guess, T., Mayhew, J., “Comparison of Reactive Strength Index Modified With and Without Arm Swing in Athletes”, 2017 National Strength and Conditioning Association (NSCA) National Conference, Las Vegas, NV, July 2017.

Larson, M., Mann, B., Ahmad, O., Burney, R., Guess, T., Jahandar, A., Razu, S., Mayhew, J., “Comparison of Static and Countermovement Push-ups in Male and Female Throwers: An Exploratory Study”, 2017 National Strength and Conditioning Association (NSCA) National Conference, Las Vegas, NV, July 2017.

Mann, B., Bird, S., Cutchlow, R., Jahandar, A., Guess, T., Mayhew, J., “Reliability of the Components of Dynamic Strength Deficit in NCAA Division-I College Baseball Players”, 2017 National Strength and Conditioning Association (NSCA) National Conference, Las Vegas, NV, July 2017.

Davis,D., Mann, B., Razu, S., Bean, K., Guess, T., “Lower Extremity Joint Kinematics: Evaluating the Differences Between Countermovement Jump Types”, Irish Journal of Medical Science, 186, S37, January 2017

Sherman, SL., Gray, A., Willis, B., Huo, Z., Siesner, N., Gulbrandsen, T., Miller, S., Razu, S., Jahandar, A., Skubic, M., Guess, TM., “Development and Validation of a Portable and Inexpensive ACL Injury Risk Identification Tool: Measuring the Drop Vertical Jump Using the Microsoft Kinect V2”, 11th Biennial International Society, of Arthroscopy, Knee Surgery, and Orthopaedic Medicine Congress, Shanghai, China, June 2017

Razu, S., Guess, T.M., “Estimation of Tibiofemoral Contact Force using Muscle Synergies”, Orthopaedic Research Society 2017 Annual Meeting, San Diego, California, March 2017

Razu, S., Sherman, S.L., Guess, T.M., “The Effect of Sulcus Angle and Tubercle Lateralization on Patellofemoral Contact Pressures during Gait: a Computational Study”, Orthopaedic Research Society 2017 Annual Meeting, San Diego, California, March 2017

Martinez C., R., Abbott, C., Prost, E., Razu, S., Guess, T.M., “Effect of Walking Poles on Trunk, Pelvic and Knee Kinematics in Older Adults”, Orthopaedic Research Society 2017 Annual Meeting, San Diego, California, March 2017

Davis L, Willis B, Gray A, Sherman S, Razu S, Jahandar A, Skubic M, Blecha K, Guess T., “Simplifying Anterior Cruciate Ligament Injury Screening: A Jump in the Right Direction.” American Physical Therapy Association Combined Sections Meeting, San Antonio, TX. February, 2017

Prost, E.L., Abbott, C., Willis, B.W., Williams, H., Flowers, P., Razu, S., Martinez Campuzano, R., Jahandar, A., Guess, T. M., “Using Walking Poles Results In Slower Gait Parameters For Community Dwelling Older Adults”, 26th Annual Caring for the Frail Elderly Conference, Columbia, MO, August 2016.

Flowers, P., Guess, T.M., “Knee Sagittal Angle and Ground Reaction Forces During Step Up Task in Knee Osteoarthritis Population Compared to Healthy Controls”, Proceedings of the 40th Annual Meeting of the American Society of Biomechanics, Raleigh, NC, August 2016

Sherman, S.L., Gulbrandsen, T.R., Miller, S.M., Guess, T.M., Willis, B.W., Blecha, K.M., Huo, Z., Skubic, M., Gray, A.D., “Mass Screening of Youth Athletes for High Risk Landing Patterns using a Portable and Inexpensive Motion Sensor Device”, American Orthopaedic Society for Sports Medicine Annual Meeting, Colorado Springs, July 2016

Razu, S., Bean, K.T., Jahandar, A., Guess, T.M., “Gender Differences Between SCoRE and Regression Methods for Locating Hip Joint Center”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Flowers, P., Guess, T.M., “Ground Reaction Forces During Step Down Task in Knee Osteoarthritis Population Compared to Healthy Controls”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Razu, S., Bean, K.T., Jahandar, A., Guess, T.M., “Comparison of Three Methods to Estimate the Axis of Rotation for the Knee”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Willis, B.W., Razu, S., Jahandar, A., Gray, A., Skubic, M., Sherman, S., Blecha, K., Guess, T.M., “Gender Differences During the Modified Star Excursion Balance Test”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Razu, S., Bean, K.T., Jahandar, A., Guess, T.M., “Kinematic Comparisons of Three Plug-in Gait Variation Protocols in Gait Analysis”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Sloan, M., Flowers, P., Guess, T.M., “Ground Reaction Forces in Healthy and Knee Osteoarthritis Populations”, Gait and Clinical Movement Analysis Society 2016 Annual Conference, Memphis, TN, May 2016

Guess, T.M., Razu, S., Jahandar, H., “Biomechanical Function of the Anterior Intermeniscal Ligament”, Orthopaedic Research Society 2016 Annual Meeting, Orlando, Florida, March 2016

Guess, T.M., Razu, S., “Function of the Deep Medial Collateral Ligament Meniscal Attachments in the ACL Deficient Knee”, Orthopaedic Research Society 2016 Annual Meeting, Orlando, Florida, March 2016

Jahandar, A., Razu, S., Jahandar, H., Nuelle, C., Guess, T.M., “Biomechanical Analysis Of The Anterolateral Ligament (ALL) Using an in vivo Musculoskeletal Model”, Orthopaedic Research Society 2016 Annual Meeting, Orlando, Florida, March 2016

Guess, T.M., Razu, S., Jahandar, H., “Effect of Deep Medial Collateral Ligaments on Meniscus Motion”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Razu, S., Mann, J. B., Guess, T.M., “Estimating Vertical and Long Jump Power in Female Collegiate Soccer Athletes”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Flowers, P., Guess, T.M., “Ground Reaction Force Comparison of Prediction-Based and Direct Measurement Systems”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Razu, S., Jahandar, A., Guess, T.M., “Comparative Evaluation of the Microsoft Kinect with the Vicon Motion Capture System to Obtain 3D Knee Angles”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Bean, K., Mann, J. B., Guess, T.M., “Lower Body Joint Kinetics in Standing Broad, Vertical, and Squat Jumps”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Flowers, P., Razu, S., Bean, K., Guess, T.M., “Kinematic Comparison of Marker-Based and Markerless Motion Capture Systems”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Jahandar, H., Razu, S. S., Sherman, S. L., Guess, T. M., “Predicting Patellofemoral Contact Mechanics: a Computational Study”, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Razu, S., Guess, T.M., “Comparison of Three Plug-in-gait Protocol Variations in Gait Analysis, Proceedings of the 39th Annual Meeting of the American Society of Biomechanics, Columbus, Ohio, August 2015

Wilson, S., Hausselle, J., Guess, T., Gonzalez, R., “Improved Contact and Meniscus Properties in Multibody Dynamics Modeling of the Knee”, XXV Congress of the International Society of Biomechanics, Glasgow, Scotland, UK, July 2015

Sherman, S. L., Razu, S. S., Jahandar, H., Guess, T. M., “’Knee cAPP’: A Musculoskeletal Model Used to Predict Changes in Patellofemoral Contact Pressures During Gait”, ICRS 2015 - 12th World Congress of the International Cartilage Repair Society, Chicago, IL, May 2015

Stylianou, A., Razu, S., Jahandar, H., Bloemker, K. H., Cil, A., Guess, T. M., “Ligament Resting Length: A Method for Patient Specific Determination.” Orthopaedic Research Society 2015 Annual Meeting, Las Vegas, Nevada, March 2015

Guess, T.M., Stylianou, A., Razu, S., Jahandar, H., “Computational Musculoskeletal Modeling in Movement Analysis”, APTA Combined Sections Meeting, Indianapolis, IN, February 2015

Guess, T.M., Stylianou, A., Jahandar, H., “Concurrent Prediction of Knee Contact, Ground Reaction, and Muscle Forces During Gait”, Proceedings of the 7th World Congress of Biomechanics, Boston, Massachusetts, July 2014

Jahandar, H., Mann, B., Guess, T. M., “Validity of the Mad Maxx Power Reading for Firing Out of the Positional Stance for American Football Players”, Scientific Program of the 2014 NSCA National Conference in Las Vegas, Nevada. July 2014, Las Vegas, NV

Wilson, S.P., Hausselle, J., Guess, T.M., Gonzalez, R.V., “Improved Multibody Modeling of Human Knee Meniscus: First-Estimate Design Techniques and Experimental Verification”, Proceedings of the 7th World Congress of Biomechanics, Boston, Massachusetts, July 2014

Rahman, M., Guess, T.M., Johnson, M., Cil, A., “Development and Validation of a Computational Multibody Model of the Elbow Joint”, Proceedings of the 37th Annual Meeting of the American Society of Biomechanics, Omaha, Nebraska, September 2013

Stylianou, A., Guess, T., Kia, M., “Tibio-Femoral Contact Pressure During Gait”, Proceedings of the ASME 2013 Summer Bioengineering Conference, Sunriver, Oregon, June 2013

Kia, M., Guess, T., Stylianou, A., “Musculoskeletal Model During treadmill Gait Session”, Proceedings of the ASME 2013 Summer Bioengineering Conference, Sunriver, Oregon, June 2013

Guess, T., Stylianou, A., Kia, M., Lu, Y., Derakhshani, R., Pulasani, P., “Concurrent Simulation of Muscle Force and Tissue Stress During Movement: Multiscale Modeling From the Body to Tissue Levels”, Proceedings of the 11th International Symposium, Computer Methods in Biomechanics and Biomedical Engineering, Salt Lake City, Utah, April 2013, Special Session: Multiscale Biomechanics: Bridging from the Body/Organ level to the Tissue/Cell/Microstructure level.

Zhu, F., Guess, T., Kia, M., “Computational Modeling to Represent Shoe Behavior in Multibody Movement Simulations”, Orthopaedic Research Society 2013 Annual Meeting, San Antonio, Texas, January 2013

Stylianou, A., Guess, T., Kia, M., “Contact Pressure Estimation in a Muscle Driven Model of an Instrumented Prosthetic Knee during Gait”, Orthopaedic Research Society 2013 Annual Meeting, San Antonio, Texas, January 2013

Kia, M., Guess, T., Stylianou, A., “Validation of a Musculoskeletal Model with Prosthetic Knee through Six Experimental Gait Trials”, Orthopaedic Research Society 2013 Annual Meeting, San Antonio, Texas, January 2013

Bloemker, K., Kia, M., Guess, T., “Prediction of Knee Loading During a Dual-Limb Squat in a Muscle-Driven Musculoskeletal Model with Anatomic Knee Joints”, Orthopaedic Research Society 2013 Annual Meeting, San Antonio, Texas, January 2013

Kia, M., Bloemker, K., Guess, T., Cil, A., “A Combined Computational and Experimental Approach to Measure the Ligament Resting Length”, Orthopaedic Research Society 2013 Annual Meeting, San Antonio, Texas, January 2013

Paiva, Gavin, Sampath Bhashyam, Ganesh Thiagarajan, Reza Derakhshani, and Trent Guess, “A Data-driven Surrogate Model to Connect Scales between Multi-domain Biomechanics Simulations” 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'12), San Diego, California, USA , August 2012

Guess, Trent M., Antonis Stylianou, and Mohammad Kia, “Validation of Knee Load Predictions During a Dual Limb Squat and Calfrise”, Proceedings of the ASME 2012 Summer Bioengineering Conference, Fajardo, Puerto Rico, June 2012

Kia, Mohammad, Guess, Trent M., and Antonis Stylianou, “Musculoskeletal Model of the Human Knee with Representation of Menisci During the Stance Phase of a Walk Cycle”, Proceedings of the ASME 2012 Summer Bioengineering Conference, Fajardo, Puerto Rico, June 2012

Guess, T. M., “Forward Dynamics Movement Simulation with Anatomical Representation of the Knee”, 10th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Berlin, Germany, April 2012

Stylianou, A. P., Guess, T. M., Cook, J. L., “Multibody Modeling of the Canine Cranial Cruciate Ligament Deficient Stifle Joint”, 2012 Veterinary Orthopedic Society Meeting, Crested Butte, Colorado, March 2012

Jacobsen, Ryan C., Trent M. Guess, and Wesley A. Burks, “Comparing Activation and Recoil Forces Generated by Epinephrine Autoinjectors and their Training Devices”, American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Conference, Orlando, Florida, March 2012

Bloemker, Katherine H., and Trent M. Guess, “Effects of ACL Reconstruction Techniques on the Kinematics of the Knee in a Computational Knee Model”, Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, Pennsylvania, June 2011

Kia, Mohammad, and Trent M. Guess, “A Musculoskeletal Model with Prosthetic Knee During a Walk Cycle”, Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, Pennsylvania, June 2011

Stylianou, Antonis, Trent M. Guess, Leo Olcott, Gavin Paiva, Mohammad Kia, James Cook, “A Model of the Canine Stifle Joint with Representation of Medial Meniscus During Squat Motion”, Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, Pennsylvania, June 2011

Paiva, Gavin, and Trent M. Guess, “Development of Generalized Parameters for Canine Multibody Meniscus Models From Experimental Data”, Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, Pennsylvania, June 2011

Trent M. Guess, “Forward Dynamics Simulation using a Natural Knee with Menisci in the Multibody Framework”, EUROMECH Colloquium 511 on Biomechanics of Human Motion. J Ambrosio et. al. (eds.), Ponta Delgada, Azores, Portugal, March, 2011

Paiva, Gavin, Trent M. Guess, Mohammad Kia, “Generating Parameters of a Multi-body Meniscus Model From Experimental Data”, Proceedings of the ASME 2010 Summer Bioengineering Conference, Naples, Florida, June 2010

Kia, Mohammad, Trent M. Guess, Gavin C. Paiva, “The Study of Menisci Effect on Tibio-Femoral Kinematics In a Computational Knee Joint”, Proceedings of the American Society of Biomechanics Annual Meeting, Penn State, Pennsylvania, August 2009

Kia, Mohammad, Trent M. Guess, Meenakshi Mishra, Ganesh Thiagarajan, “Use of Design of Experiment Approach to Predict Force-Displacement Relationship for the Subject-Specific Model of Lateral Meniscus”, Proceedings of the American Society of Biomechanics Annual Meeting, Penn State, Pennsylvania, August 2009

Kia, Mohammad and Trent M. Guess, “Use of Design of Experiment Approach to Predict Force-Displacement Relationship for the Knee Joint and Menisci in a Multi-body Dynamic Knee Model”, Proceedings of the ASME 2009 Summer Bioengineering Conference, Lake Tahoe, California, June 2009

Guess, Trent M., Mohammad Kia, Katherine Weimer, Kevin Dodd, and Lorin Maletsky, “Validation of Computational Knee Models Using a Dynamic Knee Simulator”, Proceedings of the ASME 2008 Summer Bioengineering Conference, Marco Island, Florida, June 2008

Kia, Mohammad and Trent M. Guess, “Multi-body Dynamic Simulation of the Meniscus in a Computational Knee Model”, Proceedings of the ASME 2008 Summer Bioengineering Conference, Marco Island, Florida, June 2008

Maletsky, Lorin P., Chadd W. Clary, Trent M. Guess, Amit M. Mane, Amber N. Reeve, “In Vitro Simulation of Deep Knee Flexion Using Static and Dynamic Machines”, Proceedings of the ASME 2008 Summer Bioengineering Conference, Marco Island, Florida, June 2008

Sherwood, Jesse, Reza Derakhshani, Trent Guess, “A Comparative Study of Linear and Nonlinear Data-Driven Surrogate Models of Human Joints”, Proceedings of the 2008 IEEE Region 5 Technical, Professional, and Student Conference, April 2008

Kia, Mohammad and Trent M. Guess, “The Study of Menisci Effect in a Computational Knee Model”, Proceedings of the 6th Combined Meeting of the Orthopaedic Research Societies, Honolulu, Hawaii, October 2007

Weimer, Katherine A., Trent M. Guess, Kevin A. Dodd, and Lorin P. Maletsky, “Development and Validation of a Subject-Specific Computational Human Knee Model in a Dynamic Knee Simulator Including Quadriceps Tendon and MCL Wrapping”, Proceedings of the 6th Combined Meeting of the Orthopaedic Research Societies, Honolulu, Hawaii, October 2007

Weimer, Katherine A., Trent M. Guess, Kevin A. Dodd, and Lorin P. Maletsky, “Development and Validation of a Subject-Specific Computational Human Knee Model in a Dynamic Knee Simulator”, Proceedings of the 2007 Summer Bioengineering Conference, Keystone, Colorado, June 2007

Shankar, Aarthi, and Trent M. Guess, “Optimization of Quadriceps Force Distribution for Minimization of Patellofemoral Contact Pressure During a Squat”, Proceedings of the 2007 Summer Bioengineering Conference, Keystone, Colorado, June 2007

Lenz, Nathaniel, Nicholas A Morton, Lorin P Maletsky, and Trent M. Guess, “Development Of A Cutting Maneuver To Generate A Realistic ACL Injury In Vitro”, Proceedings of the 2006 Summer Bioengineering Conference, Amelia Island, Florida, June 2006

Rayaprolu, Jyothi and Guess, Trent, “A 3-D Dynamic Model Of The Knee Joint Capable Of Controlling Quadriceps Forces Based On Predicted Retropatellar Stresses”, Proceedings of the 2005 ASME Summer Bioengineering Conference, Wayne, J. ed., Vail, Colorado, June 2005